Police said the victim, believed to have been 18, was found with a stab injury in Uxbridge Road, Shepherd’s Bush, on Wednesday night.
Scotland Yard said a murder investigation has been launched and officers are looking into the circumstances of the incident, where exactly it took place and who was involved.
Local resident Derek Parks, 64, said the teenager went to a shop and was looking for cover after an incident in the street.
He said: “The fighting happened outside the shop doorway and the gentleman came in from outside. He came into the shop for cover.
“The other guy came into the shop with the knife and stabbed him.
“The guy who got stabbed went towards the basement of the shop and was hiding.”
The knifeman ran and there was “a trail of blood” at the scene, according to Mr Parks, who has lived in the area for 40 years.
He said: “There is going to be a lot more stabbing on the streets if the Government does not take serious action. It is also down to the parents to keep a check on the children.
“Life is a precious thing which we should all treasure. All life matters.”
Shopkeeper Sully Singh said there was a police cordon in place by the time he got to the store at around 9.45pm on Wednesday after a call from his night staff.
He said: “I got a telephone call from the guys and when I came here everyone was shocked. They…
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